An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines.
نویسندگان
چکیده
A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position.
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 73 17 شماره
صفحات -
تاریخ انتشار 2008